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BENEFIX® (nonacog alfa) Indications and Usage


BeneFIX®, Coagulation Factor IX (Recombinant), is a human blood coagulation factor indicated in adults and children with hemophilia B (congenital factor IX deficiency or Christmas disease) for:

  • on-demand treatment and control of bleeding episodes
  • perioperative management of bleeding
  • routine prophylaxis to reduce the frequency of bleeding episodes

Limitation of Use

BeneFIX is not indicated for induction of immune tolerance in patients with hemophilia B [see Warnings and Precautions (5.3)].